Slide preparation of cerebrospinal fluid for cytological examination

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Slide preparation of cerebrospinal fluid for cytological examination

In liquor diagnostics, conventional liquor cytology plays an important role in the detection and classification of infectious inflammatory diseases of the CNS, in the detection of bleedings in subarachnoid spaces and in the discovery of neoplastic cells. In addition, cytological preparations are used for follow-up tests and therapy control.

As cerebrospinal fluid usually contains few cells and little albumin, cells start suffering damage a few hours after punction. Therefore, liquor samples taken to prepare slides for cytological examination should not be older than 2 hours.

Not only is the age, but also the processing of the samples of vital importance for the diagnostic value of the preparations. Good preparations of cerebrospinal fluid require optimal cell recovery and the preclusion of selective cell loss. The morphology of the cells needs to be maintained to enable a correct identification of the different cell populations.

Read more in the brochure.